ChemoID® is a proprietary second generation chemosensitivity assay that is commercially available in collaboration with Edwards Comprehensive Cancer Center and Cabell Huntington Hospital. It allows oncologists to determine how chemotherapy will impact an individual patient's cancer stem cells (CSCs) and tumor cells in the laboratory, before it is prescibed for the patient.
ChemoID was developed by Marshall University biomedical sciences researcher Dr. Pier Paolo Claudio and Jagan Valluri, PhD, a professor of Cellular Biology and Integrative Medicine at Marshall University. Much of the research was conducted at the Translational Genomics Research Institute at the Edwards Comprehensive Cancer Center in Huntington, WV.
Pier Paolo Claudio, MD, PhD, is chief scientist and president of the company. Dr. Claudio has 20 years of experience in cancer research and targeted therapy. He graduated from the University of Naples Federico II in Italy, and he has served as Associate Professor at Jefferson University Medical School and Director of the Molecular Therapy Program at Temple University.
Dr. Claudio is a pioneer in cancer research and has developed effective treatments targeted directly at cancer cells. The real groundbreaking aspect of his research is in the development of a technique to manipulate stem/progenitor cells in the lab with the goal of increasing their numbers for new stem cell-based therapies. The commercial applications of personalized chemosensitizing assays are the result of his research.
Dr. Claudio is instrumental in advancing medical research and provides leadership toward the achievement of the company's mission, strategy, annual goals and objectives. He has published over 120 scientific articles and holds numerous patents.
Dr. Claudio is an Associate Professor in the Joan C. Edwards School of Medicine at Marshall University in West Virginia, where he also serves as the Director of the Translational Genomics Research Institute (TGRI) Laboratories.
Jagan Valluri, PhD, is Vice-President and Chief Operating Officer of the company. Dr. Valluri is a Professor of Cellular Biology and Integrative Medicine at Marshall University in West Virginia. He earned his PhD in Molecular Biology from Texas A & M University. He has more than 21 years of research experience in cell culture technology and the production of anticancer bio-molecules from medicinal plant cells and bench-top fermenters.
Dr. Valluri served as a consultant for NASA and for the U.S. Army Corps of Engineers. He has authored several journal publications and book chapters, and he is the co-inventor on two patent applications. He won research innovation awards from NASA's Inventions and Contributions Board for his work on bio-production of anticancer alkaloids.
Dr. Valluri's current efforts focus on mammalian cell culture medium development and optimization, and novel cell expression systems for production of therapeutic proteins.
- Page last updated: Jul 18, 2014